Q1. Generally, karyotypes represent by arranging in the... order of size keeping their centromere in a.....
- A.Descending, straight line✓ Correct
- B.Ascending, straight line
- C.Descending, curved line
- D.Ascending, curved line
Q2. Which of the following are useful indicators to check the water quality?
- A.Phytoplankton✓ Correct
- B.Zooplankton
- C.Bacteria
- D.Fish
Q3. There are about --- loops in the chromosome of E.coli. These are highly twisted or supercoiled structure with about ---- nucleotide pairs.
- A.50, four✓ Correct
- B.100, eight
- C.50, eight
- D.100, four
Q4. Epistasis is interaction between – genes.
Q5. Stage of prophase in which nuclear membrane dissolves.
- A.Stage 5 or 1 stage✓ Correct
- B.Stage 2
- C.Stage 3
- D.Stage 4
Q6. What type of segregation occurs when alleles at the two gene loci segregate together and are transmitted as a unit?
- A.Independent segregation✓ Correct
- B.Linked segregation
- C.Random segregation
- D.Non-disjunction
Q7. Which type of inheritance appears in AB blood group phenotype?
- A.Co-dominance✓ Correct
- B.Complete dominance
- C.Incomplete dominance
- D.Recessive
Q8. According to...... genetic material parents mixes during fertilization....
- A.Blending hypothesis✓ Correct
- B.Particulate hypothesis
- C.Pangenesis
- D.Preformation
Q9. Prophase... ___________ chromosome condense and become visible
- A.I✓ Correct
- B.II
- C.III
- D.IV
Q10. Primary oocyte produces polar bodies......
Q11. Which two alleles are called co-dominant one another and are expressed when present?
- A.Allele A and Allele i✓ Correct
- B.Allele A and Allele B
- C.Allele B and Allele i
- D.Allele A and Allele O
Q12. During recessive epistasis, which color of pigeon is produced by recessive red gene with or without spread?
- A.Any color✓ Correct
- B.Red
- C.White
- D.Blue
Q13. The DNA between nucleosome is called as linker DNA. Its length is ____________
- A.20-60 bp✓ Correct
- B.10-20 bp
- C.60-100 bp
- D.100-200 bp
Q14. Mendel determined the segregation of alleles at single gene locus based on
- A.Monohybrid cross✓ Correct
- B.Dihybrid cross
- C.Test cross
- D.Back cross
Q15. Darker bands are generally found near the centromere or on the ends (telomeres) of the chromosome. The position of the dark-staining are or ___________________
- A.Heterochromatic region, heterochromatin✓ Correct
- B.Euchromatic region
- C.Centromeric region
- D.Telomeric region
Q16. During metaphase mitosis chromosome _____________________
- A.Line up at the equator✓ Correct
- B.Move to poles
- C.Condense
- D.Decondense
Q17. During stage telophase l chromosomes are.........
- A.Haploid✓ Correct
- B.Diploid
- C.Condensed
- D.Decondensed
Q18. The law of independent assortment with dihybrid cross gives genotypic ratio in F2 as:
- A.9:3:3:1✓ Correct
- B.1:2:1
- C.3:1
- D.1:1:1:1
Q19. In .... centromere splits into two parts while in..... it does not split.
- A.Mitosis, Meiosis l✓ Correct
- B.Meiosis I, Mitosis
- C.Mitosis, Meiosis II
- D.Meiosis II, Mitosis
Q20. A male bee sex is
- A.Haploid✓ Correct
- B.Diploid
- C.Triploid
- D.Polyploid
Q21. Shepherd’s purse has two shape heart and narrow. If you cross a true breeding heart to a true breeding narrow, F1 will give
- A.Narrow✓ Correct
- B.Heart
- C.Intermediate
- D.Both
Q22. The diameter of condensed scaffold associated chromatin is_____________________
- A.11 nm✓ Correct
- B.30 nm
- C.2 nm
- D.10 nm
Q23. Which of the following is not the part of Interphase in the cell cycle?
- A.M phase✓ Correct
- B.G1 phase
- C.S phase
- D.G2 phase
Q24. Which of the following is true about phosphodiester linkage?
- A.5’-phosphate group of one nucleotide unit is joined to the 3’-hydroxyl group of the next nucleotide✓ Correct
- B.3’-phosphate group joined to 5’-hydroxyl
- C.5’-phosphate joined to 5’-hydroxyl
- D.3’-phosphate joined to 3’-hydroxyl
Q25. What is the composition of nucleotide?
- A.a base + a sugar + phosphate✓ Correct
- B.a base + a sugar
- C.a sugar + phosphate
- D.a base + phosphate
Q26. Which one of the following statement is correct about human genes?
- A.30% genes in humans are di-allelic and they exist in two forms✓ Correct
- B.All genes are di-allelic
- C.Most genes are poly-allelic
- D.Genes are not allelic
Q27. The diameter of chromatin is
- A.11 nm✓ Correct
- B.30 nm
- C.2 nm
- D.10 nm
Q28. The diameter of DNA nucleosome on the chromosome scaffold is
- A.2 nm✓ Correct
- B.11 nm
- C.30 nm
- D.10 nm
Q29. Alleles separate during _____and reunite during _______
- A.Gametogenesis, Fertilization✓ Correct
- B.Mitosis, Meiosis
- C.Meiosis, Mitosis
- D.Fertilization, Gametogenesis
Q30. ____states that the two alleles of a gene found on each of a pair of chromosomes separate independently of one another into sex cells.
- A.Mendel's law of segregation✓ Correct
- B.Mendel's law of independent assortment
- C.Law of dominance
- D.Law of unit characters
Q31. The haploid cells of eukaryotes are usually known as
- A.Gametes✓ Correct
- B.Somatic cells
- C.Zygotes
- D.Spores
Q32. Which one of the following is show polygenic pattern of inheritance?
- A.All of the given✓ Correct
- B.Skin color
- C.Height
- D.Weight
Q33. How many primary molecular mechanisms of epigenetics are identified?
- A.Two✓ Correct
- B.Three
- C.Four
- D.Five
Q34. E.coli has about _____genes are organized into its one circular chromosome____
- A.3000 to 4000✓ Correct
- B.1000 to 2000
- C.4000 to 5000
- D.5000 to 6000
Q35. Pepper colour is controlled by
- A.Two genes✓ Correct
- B.One gene
- C.Three genes
- D.Four genes
Q36. ABO blood system is controlled by_
- A.A tri-allelic gene✓ Correct
- B.A di-allelic gene
- C.A single gene
- D.Multiple genes
Q37. Which one of the following statement is not correct about Co-dominance?
- A.Both alleles are expressed in a homozygous individuals✓ Correct
- B.Both alleles are expressed in heterozygous individuals
- C.Neither allele is dominant
- D.Phenotype shows both traits
Q38. Which one is not regulate gene expression?
- A.Nucleotide modification✓ Correct
- B.Histone modification
- C.DNA methylation
- D.Transcription factors
Q39. In case of two gene interaction, the gene which is masking the expression of another is called
- A.Recessive✓ Correct
- B.Dominant
- C.Epistatic
- D.Hypostatic
Q40. Which of the following is not a common mode of histone modification in eukaryotes?
- A.Sulphonation✓ Correct
- B.Acetylation
- C.Methylation
- D.Phosphorylation
Q41. Mitotic apparatus helps in..........
- A.Chromosome movement✓ Correct
- B.DNA replication
- C.Cell division
- D.Cytokinesis
Q42. The nucleosome is composed of a core of _______________histone proteins and DNA
- A.Eight✓ Correct
- B.Four
- C.Six
- D.Ten
Q43. _________bp wrapped around them.
- A.147✓ Correct
- B.146
- C.200
- D.100
Q44. Name the phenomenon which can break the occurrence of linkage?
- A.Crossing over✓ Correct
- B.Mutation
- C.Independent assortment
- D.Segregation
Q45. _trait is a stable and heritable phenotype resulting from changes in chromosome without alterations in the DNA sequence
- A.Epigenetic✓ Correct
- B.Genetic
- C.Mendelian
- D.Polygenic
Q46. Which one of the fur color of rabbit is controlled by maximum numbers of genotypes?
- A.Chinchilla✓ Correct
- B.Albino
- C.Himalayan
- D.Agouti
Q47. Which one of the following statement is not correct about genome characteristics of prokaryotes?
- A.Prokaryotes have less genome size as compared to eukaryotes✓ Correct
- B.Prokaryotes have circular DNA
- C.Prokaryotes have no introns
- D.Prokaryotes have multiple chromosomes
Q48. Inherited variations result from the
- A.Activity of genes✓ Correct
- B.Environment
- C.Chance
- D.Mutation
Q49. Which of the following is not the property of Garden Pea plant that was used by Gregor Mendel for his experiment?
- A.Long generation time✓ Correct
- B.Easy to grow
- C.Distinct traits
- D.Self-pollinating
Q50. Which comb shape is appeared when the chicken is homozygous recessive in both the R and P locus?
- A.Walnut Combs✓ Correct
- B.Single comb
- C.Pea comb
- D.Rose comb
Q51. Which sub discipline of the genetics is considered the heredity of traits in groups of individuals, but the traits of concern are determined by many genes simultaneously?
- A.Quantitative genetics✓ Correct
- B.Population genetics
- C.Molecular genetics
- D.Mendelian genetics
Q52. Which of the following organism has highest numbers of chromosome?
- A.Horsetail✓ Correct
- B.Human
- C.Fruit fly
- D.Dog
Q53. In physical map, units of distance are expressed in
- A.Base pairs or Mbs✓ Correct
- B.Centimorgans
- C.Recombination frequency
- D.Map units
Q54. When one characteristic expresses itself over the other known as
- A.Dominant✓ Correct
- B.Recessive
- C.Co-dominant
- D.Incomplete dominant
Q55. The trait that does not show through in the first generation is called
- A.Recessive✓ Correct
- B.Dominant
- C.Co-dominant
- D.Incomplete dominant
Q56. In____sister chromatids separate and move along the kinetochore microtubules toward opposite ends of the cell.
- A.Anaphase✓ Correct
- B.Metaphase
- C.Prophase
- D.Telophase
Q57. Building blocks of nucleic acids are
- A.Nucleotides✓ Correct
- B.Amino acids
- C.Monosaccharides
- D.Fatty acids
Q58. In which of the cats the pattern observed in coat colour is due to environmental effect?
- A.Siamese✓ Correct
- B.Persian
- C.Maine Coon
- D.Bengal
Q59. When one phenotypic trait is determined by multiple alleles then it is called as
- A.Pleiotropic✓ Correct
- B.Polygenic
- C.Epistatic
- D.Co-dominant
Q60. How many numbers of gene are present in Drosophila?
- A.13700✓ Correct
- B.20000
- C.25000
- D.10000
Q61. Which is a hereditary disorder characterized by lung congestion, infection and malabsorption of nutrients by the pancreas?
- A.Huntington disease✓ Correct
- B.Cystic fibrosis
- C.Sickle cell anemia
- D.Tay-Sachs
Q62. Which one following histone protein has high molecular weight, greater number of amino acid and high percentage of lysine and arginine?
- A.H1✓ Correct
- B.H2A
- C.H2B
- D.H3
Q63. Which of the following blood group is considered a universal donor?
Q64. Which statement is correct about genetic and physical mapping?
- A.The some genes are close together on the genetic map and also are close together on the physical map of the chromosome✓ Correct
- B.Genetic and physical maps are always identical
- C.Physical map uses recombination frequency
- D.Genetic map uses base pairs
Q65. Polygenic traits are also affected by the persons environment, so they are called
- A.Multifactorial✓ Correct
- B.Mendelian
- C.Single gene
- D.Dominant
Q66. Which is a histone deacetylase inhibitor?
- A.vorinostat✓ Correct
- B.trichostatin A
- C.sodium butyrate
- D.valproic acid
Q67. The spindle apparatus is formed during the phase of mitosis.
- A.Prophase✓ Correct
- B.Metaphase
- C.Anaphase
- D.Telophase
Q68. During, _ the effects of prophase and pro-metaphase are reversed
- A.Telophase✓ Correct
- B.Anaphase
- C.Metaphase
- D.Cytokinesis
Q69. Meiosis results in, _____________
- A.4 diploid daughter cells✓ Correct
- B.4 haploid daughter cells
- C.2 diploid daughter cells
- D.2 haploid daughter cells
Q70. The allelic series refers to
- A.Multiple alleles✓ Correct
- B.Two alleles
- C.Dominant alleles
- D.Recessive alleles
Q71. The crossing-over occurs at
- A.Chiasmata✓ Correct
- B.Centromere
- C.Telomere
- D.Nucleosome
Q72. Which one of following statement is not correct about continuous variation?
- A.Continuous variation controlled by a lot of genes✓ Correct
- B.Continuous variation shows distinct categories
- C.Continuous variation is polygenic
- D.Continuous variation is influenced by environment
Q73. have the same length, shape, centromere location, and genes
- A.Paired chromosomes✓ Correct
- B.Homologous chromosomes
- C.Sister chromatids
- D.Non-homologous chromosomes
Q74. Mutational changes are..... and epigenetic changes can be.....
- A.Irreversible, Reversible✓ Correct
- B.Reversible, Irreversible
- C.Both irreversible
- D.Both reversible
Q75. Position dependent method of diseased gene identification follows
- A.Reverse genetics✓ Correct
- B.Forward genetics
- C.Genome-wide association
- D.Linkage analysis
Q76. Which statement is not correct about epigenetic regulation in identical twins?
- A.The epigenetic tags can have such an effect on the twins that one can develop a disease and the other is also✓ Correct
- B.Epigenetic differences increase with age
- C.Twins have identical epigenomes at birth
- D.Environment can cause epigenetic changes
Q77. Which one of the following genotype expresses the Green color of pepper?
- A.rr/yy✓ Correct
- B.Rr/Yy
- C.RR/YY
- D.rr/YY
Q78. Which one of following statement is correct?
- A.Father with X-linked disorder will transmit the mutant allele to all daughters but to no sons✓ Correct
- B.Father with X-linked disorder will transmit to all sons
- C.Mother with X-linked disorder will transmit to all daughters
- D.X-linked disorders are always dominant
Q79. Band that indicates constitutive heterochromatin
- A.C band✓ Correct
- B.G band
- C.R band
- D.Q band
Q80. What is the process of transfer of human blood known as?
- A.Transfusion✓ Correct
- B.Transplantation
- C.Transduction
- D.Transformation
Q81. All offspring of same variety is called as
- A.True breed✓ Correct
- B.Hybrid
- C.Pure line
- D.Strain
Q82. In DNA double helix, the two DNA chains are held together by
- A.Hydrogen bonds between the pair of bases✓ Correct
- B.Covalent bonds
- C.Ionic bonds
- D.Phosphodiester bonds
Q83. Darker bands are generally found near the centromere or on the ends (telomeres) of the chromosome. The position of the dark-staining are
- A.Heterochromatic region, heterochromatin✓ Correct
- B.Euchromatin region, euchromatin
- C.Euchromatin region, heterochromatin
- D.Heterochromatic region, euchromatin
Q84. During stage telophase I, chromosomes are...
- A.Haploid✓ Correct
- B.Diploid
- C.Condensed
- D.Decondensed
Q85. Who is considered "The Father of Genetics"?
- A.Gregor Mendel✓ Correct
- B.Charles Darwin
- C.Thomas Morgan
- D.Watson and Crick
Q86. is an example of inherited variation.
- A.Eye color
- B.Height
- C.Fingerprints✓ Correct
- D.Blood type
Q87. When chromosomes stained they show a dark-stained region that is the
- A.Centromere✓ Correct
- B.Telomere
- C.Nucleosome
- D.Chromatin
Q88. Histones have two basic amino acids .
- A.Arginine-lysine✓ Correct
- B.Histidine-arginine
- C.Lysine-histidine
- D.Arginine-histidine
Q89. Which type of genetics deals with movement of genes and genetic traits from parents to offspring?
- A.Transmission genetics✓ Correct
- B.Molecular genetics
- C.Population genetics
- D.Developmental genetics
Q90. Accordingto__________ genetic material of the parents mixes during fertilization
- A.Particulate hypothesis
- B.Blending hypothesis✓ Correct
- C.Either blending hypothesis or Particulate hypothesis
- D.Neither blending hypothesis nor Particulate hypothesis
Q91. Which one of following statements is correct about to the Mendel Law of Dominance?
- A.In a cross of parents that are pure for contrasting traits only one form of the trait will appear in the next generation✓ Correct
- B.In a cross of parents that are pure for contrasting traits blended form of the trait will appear in the next generation
- C.In a cross of parents that are pure for contrasting traits two form of the traits will appear in the next generation
- D.In a cross of parents that are pure for contrasting traits no form of the traits will appear in the next generation
Q92. During the summer, the arctic fox produces enzymes that cause its fur to become reddish brown. During the winter, these enzymes do not function. As a result, the fox has a white coat that blends into the snowy background. This change in fur color shows that:
- A.The expression of certain genes is affected by temperature✓ Correct
- B.Random alteration of DNA can occur on certain chromosomes
- C.The genes of a fox are made of unstable DNA
- D.Mutations can be caused by temperature extremes
Q93. According to particulate hypothesis, parents pass on distinct heritable units. Those distinct heritable units are now called as
- A.Genes✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q94. About 90% of the time taken for meiosis is required for
- A.Prophase I✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q95. How much length of the DNA sequence within kinetochores regions?
- A.120bp✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q96. What is the unit of linkage map?
- A.Centi-morgan✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q97. Due to during meiosis I, the two sister chromatids of each chromosome are no longer genetically identical
- A.Crossing over✓ Correct
- B.Metaphase plate
- C.Option3
- D.Option4
Q98. DNA replication is a type of
- A.Semiconservative✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q99. Which one of the following statement about prokaryotic chromosome is wrong?
- A.Prokaryotes have single chromosome plus plasmids
- B.Prokaryotic chromosome made of DNA and Histone proteins✓ Correct
- C.Prokaryotic chromosome found in cytoplasm
- D.Option4
Q100. Which is the cause of epigenetics?
- A.Option1✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q101. Identify the purine base of nucleic acids in the following
- A.Adenine✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q102. The diameter of packed nucleosome is
- A.Option1✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q103. Technique that gives a rough idea of gene location
- A.Genetic mapping✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q104. Fragile X chromosome affects the ______ gene.
- A.FMR1✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q105. How many numbers of alleles control the fur color of rabbit?
- A.4✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q106. The ABO blood group in humans is determined by
- A.Multiple alleles✓ Correct
- B.Option2
- C.Option3
- D.Option4
Q107. The giant chromosomes found in _____ and they may be as long as 300 _____ and up to 10 _____ in diameter.
- A.Diptera✓ Correct
- B.Lepidoptera
- C.Hymenoptera
- D.Coleoptera
Q108. Which map is primarily based on the locations of landmarks along a DNA molecule?
- A.Physical map✓ Correct
- B.Genetic map
- C.Linkage map
- D.Cytogenetic map
Q109. Genetic make-up of an organism is called
- A.Genotype✓ Correct
- B.Phenotype
- C.Allele
- D.Gene
Q110. The type of cell division important for tissue regeneration is
- A.Mitosis✓ Correct
- B.Meiosis
- C.Binary fission
- D.Budding
Q111. Chromosomes were described by _____ in 1875 and chromosome was first used by _____ in 1888
- A.Strausberger, Waldeyer✓ Correct
- B.Francis Crick, James Watson
- C.Thomas H. Morgan, Daniel Nathans
- D.Mendel, Darwin
Q112. During prophase, the nuclear envelope _____
- A.Disappears✓ Correct
- B.Reappears
- C.Thickens
- D.Duplicates
Q113. _____ occurs when one mutation has the opposite effect when in the presence of another mutation.
- A.Sign epistasis✓ Correct
- B.Reciprocal sign epistasis
- C.Compensatory mutation
- D.Synthetic lethality
Q114. Which of the following has longer chromosomes?
- A.Plants✓ Correct
- B.Animals
- C.Fungi
- D.Bacteria
Q115. A heredity unit on chromosomes is called:
- A.Gene✓ Correct
- B.Allele
- C.Locus
- D.Chromatid
Q116. Which one of the following is not correct about the influence of environmental factors on epigenetics?
- A.Social interactions and physical activity not affect the epigenome✓ Correct
- B.Diet can affect epigenome
- C.Stress can affect epigenome
- D.Toxins can affect epigenome
Q117. Name the organism whose first genetic map was made?
- A.Drosophila✓ Correct
- B.E. coli
- C.Neurospora
- D.Maize
Q118. Which one of the statement is not correct about the position dependent method of disease causing gene mapping in human?
- A.Starting from the approximate location of the gene, to finding the gene itself
- B.Starting at the phenotype, determining which protein was involved and then getting to the gene through the protein✓ Correct
- C.Translating it to learn about the protein and its function
- D.Positional cloning or reverse genetics
Q119. Which is the correct sequence of Bottom up mapping technique?
- A.Make random clones— Sequence each clone— Overlap sequence reads— Overlap contigs for complete sequence.✓ Correct
- B.Overlap contigs for complete sequence — Sequence each clone —Make random clones— Overlap sequence reads.
- C.Sequence each clone— Overlap sequence reads— Overlap contigs for complete sequence— Make random clones
- D.Overlap sequence reads— Overlap contigs for complete sequence— Sequence each clone— Make random clones
Q120. The numbers of genotypes can be calculated on the basis of
- A.Number of alleles✓ Correct
- B.Number of genes
- C.Number of chromosomes
- D.Number of loci
Showing the first 120 of 166 MCQs.